The TS score has the desirable property that it gets higher as the primary and secondary isoforms expression profiles becomes both more dissimilar in shape, and
The TS score has the desirable property that it gets higher as the primary and secondary isoforms expression profiles becomes both more dissimilar in shape, and more distinct in terms of their overall gene expression magnitudes. This diversification in profiles not only helps in distinguishing between different isoforms more clearly but also aids in understanding the functionality and the regulatory mechanisms that might differ between them. By leveraging the TS score, researchers can more accurately identify which isoforms are likely to be influential in specific cellular contexts, which is crucial for developments in genetic research and therapeutic interventions.
